Endocrinology-metabolism
Obstructive sleep apnea with excessive daytime sleepiness is associated with non-alcoholic fatty liver disease regardless of visceral fat
Ji Hee Yu, Jae Hee Ahn, Hye Jin Yoo, Ji A Seo, Sin Gon Kim, Kyung Mook Choi, Sei Hyun Baik, Dong Seop Choi, Chol Shin, Nan Hee Kim
Korean J Intern Med. 2015;30(6):846-855. Published online October 30, 2015
Background/Aims: Obstructive sleep apnea (OSA) is associated with an increased risk of obesity and non-alcoholic fatty liver disease (NAFLD), but it remains unclear whether the risk of NAFLD is independently related to OSA regardless of visceral obesity. Thus, the aim of the present study was to exa..
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Infectious diseases
Clinical significance of methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci colonization in liver transplant recipients
Youn Jeong Kim, Sang Il Kim, Jong Young Choi, Seung Kyu Yoon, Young-Kyoung You, Dong Goo Kim
Korean J Intern Med. 2015;30(5):694-704. Published online August 27, 2015
Background/Aims: Liver transplant patients are at high risk for methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE) colonization. We evaluated patients before and after liver transplant using active surveillance culture (ASC) to assess the prevalence ..
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Gastroenterology
Mesenchymal stem cell therapy for liver fibrosis
Young Woo Eom, Kwang Yong Shim, Soon Koo Baik
Korean J Intern Med. 2015;30(5):580-589. Published online August 27, 2015
Currently, the most effective treatment for end-stage liver fibrosis is liver transplantation; however, transplantation is limited by a shortage of donor organs, surgical complications, immunological rejection, and high medical costs. Recently, mesenchymal stem cell (MSC) therapy has been suggested ..
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Prevalence of and risk factors for endogenous endophthalmitis in patients with pyogenic liver abscesses
In Hyung Park, Chung Hwan Jun, Jin Woo Wi, Seon Young Park, Wan Sik Lee, Sook In Jung, Chang Hwan Park, Young Eun Joo, Hyun Soo Kim, Sung Kyu Choi, Jong Sun Rew
Korean J Intern Med. 2015;30(4):453-459. Published online June 29, 2015
Background/Aims: Although pyogenic liver abscesses (PLAs) can be successfully treated, the visual prognosis of patients with endogenous endophthalmitis (EE) associated with a PLA is poor. Early diagnosis and prompt intervention may salvage useful vision. Therefore, we investigated risk factors for E..
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Eosinophilic organ infiltration without
eosinophilia or direct parasite infection
Il Young Jang, Young-Joo Yang, Hyung Jin Cho, Yunsik Choi, Eun-Hye Shin, Dong-Uk Kang, Tae-Bum Kim
Korean J Intern Med. 2014;29(1):126-129. Published online January 2, 2014
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Gastroenterology
Is propofol safe when administered to cirrhotic patients during sedative endoscopy?
Sang Jun Suh, Hyung Joon Yim, Eileen L. Yoon, Beom Jae Lee, Jong Jin Hyun, Sung Woo Jung, Ja Seol Koo, Ji Hoon Kim, Kyung Jin Kim, Rok Son Choung, Yeon Seok Seo, Jong Eun Yeon, Soon Ho Um, Kwan Soo Byun, Sang Woo Lee, Jai Hyun Choi, Ho Sang Ryu
Korean J Intern Med. 2014;29(1):57-65. Published online January 2, 2014
Background/Aims: In patients with liver cirrhosis, drugs acting on the central
nervous system can lead to hepatic encephalopathy and the effects may be prolonged.
Recently, misuse of propofol has been reported and the associated risk of
death have become an issue. Propofol is commonly used during..
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Effects of D-002, a mixture of high molecular weight beeswax alcohols, on patients with nonalcoholic fatty liver disease
José Illnait, Iván Rodríguez, Sarahí Mendoza, Yolanda Fernández, Rosa Mas, Mirtha Miranda, Jesús Piñera, Julio César Fernández, Meilis Mesa, Lilia Fernández, Daisy Carbajal, Rafael Gámez
Korean J Intern Med. 2013;28(4):439-448. Published online July 1, 2013
Background/AimsNonalcoholic fatty liver disease (NAFLD) is intimately related to insulin resistance and ranges from a benign course to liver fibrosis and cirrhosis. NAFLD management mainly involves dietary modification and weight loss. Although no fully successful pharmacologi..
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Cardiology
Serum bilirubin as a prognostic marker in patients with acute decompensated heart failure
Jayakrishna Chintanaboina, Matthew S. Haner, Arjinder Sethi, Nimesh Patel, Walid Tanyous, Alexander Lalos, Sameer Pancholy
Korean J Intern Med. 2013;28(3):300-305. Published online May 1, 2013
Background/AimsSeveral prognostic markers for heart failure (HF) have been determined but the importance of liver function tests (LFTs) remains unknown. The aim of this study was to determine the prognostic significance, if any, of abnormal LFTs in acute decompensated HF. <..
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Gastroenterology
Clinical characteristics and the usefulness of the QuantiFERON-TB Gold In-Tube test in hematologic patients with hepatic or splenic lesions
Jae-Cheol Kwon, Si-Hyun Kim, Sun Hee Park, Su-Mi Choi, Dong-Gun Lee, Jung-Hyun Choi, Jin-Hong Yoo, Yoo-Jin Kim, Seok Lee, Hee-Je Kim, Seok-Goo Cho, Jong-Wook Lee, Woo-Sung Min
Korean J Intern Med. 2013;28(2):187-196. Published online February 27, 2013
Background/AimsHepatic or splenic lesions in hematologic patients are not defined well because they are not easy to evaluate due to limitations of invasive procedures. Management typically depends on the clinical diagnosis with few microbiological data. Me..
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Pelvic Bone Fractures Mimicking Bone Metastases in a Patient with Hepatitis B Virus-Associated Liver Cirrhosis and Hepatocellular Carcinoma
Dong Hyeon Lee, Eun Sun Jang, Hong Sang Oh, Kwang Hyun Chung, Eun Hyo Jin, Eu Jeong Ku, Eun Roh
Korean J Intern Med. 2012;27(4):467-469. Published online November 27, 2012
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Status Quo of Chronic Liver Diseases, Including Hepatocellular Carcinoma, in Mongolia
Amarsanaa Jazag, Natsagnyam Puntsagdulam, Jigjidsuren Chinburen
Korean J Intern Med. 2012;27(2):121-127. Published online May 31, 2012
Because Mongolia has much higher liver disease burden than any other regions of the world, it is necessary to provide information on real-time situation of chronic liver disease in Mongolia. In this article, we reviewed studies performed in Mongolia from 2000 to 2011 on seroprevalence of hepatiti..
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Albumin for End-Stage Liver Disease
June Sung Lee
Korean J Intern Med. 2012;27(1):13-19. Published online February 28, 2012
Albumin has been widely used in patients with cirrhosis in an attempt to improve circulatory and renal functions. The benefits of albumin infusions in preventing the deterioration in renal function associated with large-volume paracentesis, spontaneous bacterial peritonitis, and established hepat..
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Usefulness of C-Reactive Protein for Evaluating Clinical Outcomes in Cirrhotic Patients with Bacteremia
Young Eun Ha, Cheol-In Kang, Eun-Jeong Joo, Mi-Kyong Joung, Doo Ryeon Chung, Kyong Ran Peck, Nam Yong Lee, Jae-Hoon Song
Korean J Intern Med. 2011;26(2):195-200. Published online June 1, 2011
Background/AimsThe purpose of this study was to evaluate the value of initial C-reactive protein (CRP) as a predictor of clinical outcome and to investigate whether follow-up CRP measurement is useful for the prediction of the clinical outcome of bloodstream infections in pati..
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Increased Expression of Cyclooxygenase-2 is Associated with the Progression to Cirrhosis
Soung Won Jeong, Jae Young Jang, Sae Hwan Lee, Sang Gyun Kim, Young Koog Cheon, Young Seok Kim, Young Deok Cho, Hong Soo Kim, Joon Seong Lee, So-Young Jin, Chan Sup Shim, Boo Sung Kim
Korean J Intern Med. 2010;25(4):364-371. Published online November 27, 2010
Background/AimsTo investigate the degree of cyclooxygenase-2 (COX-2) protein expression in chronic hepatitis and cirrhosis. MethodsCOX-2 protein expression was evaluated in 43 cases of chronic hepatitis and 24 cases of cirrhosis using immunohist..
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The Association Between the Serum Sodium Level and the Severity of Complications in Liver Cirrhosis
Jong Hoon Kim, June Sung Lee, Seuk Hyun Lee, Won Ki Bae, Nam-Hoon Kim, Kyung-Ah Kim, Young-Soo Moon
Korean J Intern Med. 2009;24(2):106-112. Published online June 8, 2009
Background/AimsDilutional hyponatremia associated with liver cirrhosis is caused by impaired free water clearance. Several studies have shown that serum sodium levels correlate with survival in cirrhotic patients. Little is known, however, regarding the relationship between th..
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Spontaneous rupture of the lateral thoracic artery in patients with liver cirrhosis
Tae Hee Lee, Yong Sung Park, Dong Jin Chung, Ji Hyung Kim, Sun Moon Kim, Euyi Hyeog Im, Kyu Chan Huh
Korean J Intern Med. 2008;23(3):152-155. Published online September 20, 2008
Bleeding in patients with liver cirrhosis is primarily caused by gastroesophageal varix in association with extensive collateral circulation, portal hypertensive gastropathy, a Mallory-Weiss tear and peptic ulcer disease. The spontaneous rupture of an artery, as a result of coagulopathy, is extre..
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Helicobacter pylori Infection and Peptic Ulcer Disease in Patients with Liver Cirrhosis
Dong Joon Kim, Hak Yang Kim, Sung Jung Kim, Tae Ho Hahn, Myoung Kuk Jang, Gwang Ho Baik, Jin Bong Kim, Sang Hoon Park, Myung-Seok Lee, Choong Kee Park
Korean J Intern Med. 2008;23(1):16-21. Published online March 20, 2008
Background/AimsWe investigated the prevalence and relationship of peptic ulcer disease and Helicobacter pylori infection to liver cirrhosis. MethodsWe examined 288 patients with liver cirrhosis, 322 patients w..
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Comparison of the Applicability of Two Prognostic Scoring Systems In Patients with Fulminant Hepatic Failure
Won-Choong Choi, Walid C. Arnaout, Federico G. Villamil, Achilles A. Demetriou, John M. Vierling
Korean J Intern Med. 2007;22(2):93-100. Published online June 30, 2007
BackgroundDistinguishing those patients with fulminant hepatic failure (FHF) and who require transplantation from those FHF patients who will survive with receiving only intensive medical care remains problematic, and this distinction is important because of the chronic shorta..
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Capecitabine and Oxaliplatin (XELOX) for the Treatment of Patients with Metastatic Gastric Cancer and Severe Liver Dysfunction
Seung Jae Hwang, Jong Won Park, Sehe Dong Lee, Gyong Jung Kim, Cheol Ho Sin, Seung-Hyun Nam, Bong-Seog Kim
Korean J Intern Med. 2006;21(4):252-255. Published online December 31, 2006
Gastric cancer patients with severe liver dysfunction secondary to hepatic metastases have limited treatment options. Most cytotoxic drugs have a narrow therapeutic index. Although both capecitabine and oxaliplatin have been well tolerated as single agents for patients with severe hepatic dysfunc..
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A Case of Multiple Organ Failure due to Heat Stoke Following a Warm Bath
Seung Young Kim, Su Ah Sung, Gang Jee Ko, Chang Su Boo, Sang Kyung Jo, Won Yong Cho, Hyoung Kyu Kim
Korean J Intern Med. 2006;21(3):210-212. Published online September 30, 2006
Heat stroke is a potentially fatal disorder that's caused by an extreme elevation in body temperature. We report here an unusual case of multiple organ failure that was caused by classical, nonexertional heat stroke due to taking a warm bath at home. A 68 year old diabetic man was hospitalized fo..
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